Publications

Project: Hamilton Emerging Adult Life Transitions and Health Imaging Investigation (HEALTH‑II) 

Principal Investigator: James MacKillop 

Elsayed, Mahmoud, et al. “Machine Learning‑Based Computational Validation of the Addictions Neuroclinical Assessment Framework in Relation to Hazardous Drinking.” Journal of Psychiatry and Neuroscience (2026). 

Deng, Wei Q., et al. “Genome‑Wide Association Studies of Delay Discounting and Impulsive Personality Traits in Children from the Adolescent Brain Cognitive Development Study.” Genes, Brain and Behavior 24.4 (2025): e70033. 

Elsayed, Mahmoud, et al. “Empirical Examination of Working Memory Performance and Its Neural Correlates in Relation to Delay Discounting in Two Large Samples.” Behavioural Brain Research 475 (2024): 115217. 

Xu, Hui, Max M. Owens, and James MacKillop. “Neuroanatomical Profile of BMI Implicates Impulsive Delay Discounting and General Cognitive Ability.” Obesity 31.11 (2023): 2799–2808. 

Xu, Hui, James MacKillop, and Max M. Owens. “A Machine Learning‑Derived Neuroanatomical Pattern Predicts Delayed Reward Discounting in the Human Connectome Project Young Adult Sample.” Journal of Neuroscience Research 101.7 (2023): 1125–1137.

Project: Correlating Advanced Magnetic Resonance Imaging (MRI) Metrics with Single Nucleotide Polymorphisms (SNPs) to Assess and Predict Recovery from Mild Traumatic Brain Injury (mTBI) 

Principal Investigator: Michael Noseworthy, Dinesh Kumbhare, Julian Dobranowski 

Doughty, Mitchell, et al. “Years of play alter MRI measures of brain health in former Canadian Football League athletes: a pilot study.” Journal of Concussion 7 (2023): 20597002231200372. 

Tajik, Mahnaz, and Michael D. Noseworthy. “A review of molecular and genetic factors for determining mild traumatic brain injury severity and recovery.” Brain Disorders 8 (2022): 100058. 

Danielli, Ethan, et al. “Functional, but minimal microstructural brain changes present in aging Canadian football league players years after retirement.” Brain Disorders 6 (2022): 100036. 

Polak, Paul, Rolf F. Schulte, and Michael D. Noseworthy. “An approach to evaluation of the point‐spread function for 23Na magnetic resonance imaging.” NMR in Biomedicine 35.2 (2022): e4627. 

McGillivray, Joshua E., et al. “The effect of exercise on neural activation and cognition: a review of task-based fMRI studies.” Critical Reviews™ in Biomedical Engineering 49.2 (2021). 

Stillo, David, et al. “Localization and identification of brain microstructural abnormalities in paediatric concussion.” Frontiers in human neuroscience 15 (2021): 657374. 

Nowikow, Cameron E., et al. “Network and Field Analysis of Koch Snowflake Fractal Geometry Radiofrequency Coils for Sodium MRI.” Frontiers in Physics 9 (2021): 697104. 

McCrindle, Brian, et al. “A radiology-focused review of predictive uncertainty for AI interpretability in computer-assisted segmentation.” Radiology: Artificial Intelligence 3.6 (2021): e210031. 

Danielli, Ethan, et al. “A review of MRI and exercise treatment for improved concussion diagnosis and recovery.” Critical Reviews™ in Biomedical Engineering 48.5 (2020).

Project: Building a Deep‑Learning Healthcare System in Child and Youth Mental Health 

Principal Investigators: Roberto Sassi, Paulo Pires, Laura Duncan 

Saggu, Simran, et al. “Prediction of Emergency Department Revisits among Child and Youth Mental Health Outpatients Using Deep Learning.” BMC Medical Informatics and Decision Making 24.1 (2024): 42. 

Daneshvar, Hirad, et al. “SOK: Application of Machine Learning Models in Child and Youth Mental Health Decision‑Making.” Artificial Intelligence for Medicine (2024): 113–132. 

Boyle, Michael H., et al. “Problem Checklists and Diagnostic Interviews: Evidence of Psychometric Equivalence.” Journal of Child Psychology and Psychiatry 64.5 (2023): 779–786. 

Duncan, Laura, et al. “Estimating Prevalence of Child and Youth Mental Disorder and Mental Health‑Related Service Contacts: A Comparison of Survey Data and Linked Administrative Health Data.” Epidemiology and Psychiatric Sciences 31 (2022): e35. 

Duncan, Laura, et al. “Development and Psychometric Evaluation of a Teacher Version of the Ontario Child Health Study Emotional Behavioural Scales (OCHS‑EBS‑T).” Psychiatry Research 312 (2022): 114574. 

Edwards, Jordan, et al. “Characterizing Mental Health‑Related Service Contacts in Children and Youth.” Child and Adolescent Psychiatry and Mental Health 16.1 (2022): 48. 

Ferro, Mark A., et al. “Mental and Psychosocial Health among Youth after Their First Psychiatric Hospitalization.” BMC Research Notes 15.1 (2022): 233. 

Project: The Epidemiology of SARSCoV2 Infection Risk Among Retirement Homes in Ontario 

Principle investigator: Dr. Andrew Costa 

Zhang, Ali, et al. “Antibody responses to third-dose mRNA vaccines in nursing home and assisted living residents.” Journal of the American Medical Directors Association 23.3 (2022): 444-446. 

Costa, Andrew P., et al. “Risk factors for outbreaks of SARS-CoV-2 infection at retirement homes in Ontario, Canada: a population-level cohort study.” CMAJ 193.19 (2021): E672-E680. 

Manis, Derek R., et al. “Examining Health Service Rates Among Residents of Retirement Homes and Other Older Adult Populations in Ontario, Canada: A Population-Based Cohort Study.” medRxiv (2021): 2021-09. 

Project: Post‑Surgery Virtual Care with Remote Automated Monitoring Technology‑2 (PVC‑RAM‑2) 

Principal Investigators: P. J. Devereaux, Michael McGillion 

McGillion, Michael H., et al. “Continuous noninvasive remote automated blood pressure monitoring with novel wearable technology: a preliminary validation study.” JMIR mHealth and uHealth 10.2 (2022): e24916. 

McGillion, Michael H., et al. “Beyond wellness monitoring: continuous multiparameter remote automated monitoring of patients.” Canadian Journal of Cardiology 38.2 (2022): 267-278. McGillion, M. H., et al. (2021). 

McGillion, Michael H., et al. “Post-discharge after surgery Virtual Care with Remote Automated Monitoring-1 (PVC-RAM-1) technology versus standard care: randomised controlled trial.” BMJ  374 (2021). 

McGillion, Michael, et al. “Postoperative remote automated monitoring and virtual hospital-to-home care system following cardiac and major vascular surgery: user testing study.” Journal of Medical Internet Research 22.3 (2020): e15548. 

McGillion, Michael H., et al. “Detection of Postoperative Vital Signs Abnormalities on a Surgical Ward Using Conventional and Remote Automated Monitoring.” Canadian Journal of General Internal Medicine 17.S1 (2022): 17–27. 

McGillion, Michael H., et al. “Risk Factors for Hospital Readmission Following Noncardiac Surgery: International Cohort Study.” Annals of Surgery Open 5.2 (2024): e417. 

Project: Medical Masks versus N95 Respirators to Prevent COVID‑19 

Principal Investigator: Mark Loeb 

Loeb, Mark, et al. “Medical Masks versus N95 Respirators for Preventing COVID‑19 among Health Care Workers.” Annals of Internal Medicine 175.12 (2022): 1629–1638. 

Project: SERENE – Severe Maternal Morbidity Prevention and Care Model 

Principal Investigators: Giulia Muraca, Benicio N. Frey, Rohan D’Souza, Sheryl Green, Susan Jack 

Hicks, Amanda, et al. “Health Care Experiences and Expectations of Individuals with Severe Maternal Morbidity.” JBI Evidence Synthesis 23.8 (2025): 1633–1645. 

Rajasingham, Maya, et al. “Severe Maternal Morbidity from Conception to Six Weeks Postpartum in Ontario.” Canadian Medical Association Journal 198.10 (2026): E344–E357. 

Project: Burn Research Program 

Principal Investigator: Marc G. Jeschke 

Khalaf, Fadi, et al. “Burn Injuries Accelerate Biological Aging and Increase the Epigenetically Inferred Risk of Mortality and Frailty.” Aging Disease (2025). 

Barayan, Dalia, et al. “Metformin Administration Improves Adverse Outcomes in Older Adult Burn Patients.” NPJ Aging 11.1 (2025): 43. 

Elloso, Margarita, et al. “Challenges of Porcine Wound Models: A Review.” International Journal of Translational Medicine 5.1 (2025): 4. 

Douglas, Alisa, et al. “Bioprinting‑by‑Design of Hydrogel‑Based Biomaterials for In Situ Skin Tissue Engineering.” Gels 11.2 (2025): 110. 

Khalaf, Fadi, et al. “Metabolaging: A New Geroscience Perspective Linking Aging Pathologies and Metabolic Dysfunction.” Metabolism 166 (2025): 156158. 

Loft, Anne, et al. “Towards a Consensus Atlas of Human and Mouse Adipose Tissue.” Nature Metabolism 7.5 (2025): 875–894. 

Aijaz, Ayesha, et al. “A Bio‑Instructive, Bioactive In Situ Polymerizable Wound Matrix Promotes Scar‑Free Burn Repair.” iScience 28.5 (2025). 

Rehou, Sarah, et al. “Trajectories of Survivors and Non‑Survivors Post‑Burn Injury.” Annals of Surgery (2025). 

Farahat, Mahmoud, et al. “Human iPSCs‑Derived Mesenchymal Stem Cells Promote Skin Regeneration and Burn Wound Healing.” NPJ Regenerative Medicine 10.1 (2025): 40. 

Tedesco, Diana Julia, et al. “Sepsis in Burn Care: Incidence and Outcomes.” Military Medical Research 12.1 (2025): 55. 

Tedesco, Diana Julia, et al. “Sex‑ and Age‑Related Differences in Post‑Burn Pathophysiology.” Critical Care Medicine 53.10 (2025): e1941–e1951. 

Bhattachan, Punit, et al. “The Role of Artificial Intelligence in Burn Assessment, Diagnosis and Outcome Prediction.” Burns & Trauma (2025). 

Bhattachan, Punit, et al. “Burn Injury Triggers Distinct Transcriptomic Profiles in Adipose Tissue of Adult and Aged Mice.” The FASEB Journal 39.17 (2025): e71024.